Angelman syndrome is a complex genetic disorder that affects the nervous system and causes severe physical and intellectual disability.
The life expectancy for those living with Angelman Syndrome appears normal although they will require life-long care. AS affect all races and both genders equally.
Angelman syndrome is a disorder not a disease, and at present there is no specific therapy for AS. Medical therapy for seizures is usually necessary. Physical and occupational therapies, communication therapy and behavioural therapies are important in allowing individuals to each their maximum developmental potential.
Typical characteristics of Angelman syndrome include:
Delayed development (usually noticeable from 6-12 months of age)
Severe language impairment with little or no speech
In most cases, Angelman syndrome isn’t inherited from your parents, and the genetic anomaly responsible for the syndrome occurs by chance around the time of conception. However, in some families, more than one child is affected.
The typical characteristics of Angelman syndrome aren’t usually apparent at birth. A child with the syndrome will begin to show signs of delayed development around 6-12 months, such as being unable to sit unsupported or make babbling noises. Later, they may not speak at all or may only be able to say a few words.